Scientific Program

Conference Series LLC Ltd invites all the participants across the globe to attend 3rd International Conference on Pharmaceutical Research
&
Innovations in Pharma Industry | Barcelona, Spain.

Day 2 :

Keynote Forum

Muhammad Jehangir

Novamed Group, Pakistan

Keynote: Stability indicating by HPLC method development and validation

Time : 10:00-10:45

Pharma Research 2020 International Conference Keynote Speaker Muhammad Jehangir photo
Biography:

Muhammad Jehangir has 15 years diversifi ed experience of quality control, quality assurance, registra on aff airs, product development and pharmaceu cal manufacturing, process planning, method development, method valida on, sta s cal methodology, process & cleaning valida on, and equipment valida on etc. Cer fi cate courses on cGMP, cGLP, process valida on, CTD Documents, ISO 9001:2008, 13485-2003, 14001-2004 and 17025:2017 have strong scien fi c, analy cal, sta s cal, managerial and training skills. Currently, he is working as a Senior Manager Quality Control and valida on for Novamed Pharmaceu cals, Pakistan. It is toll manufacturing oriented company, manufacturing of companies like Getz Pharma, ICI, SEARLE, Macter, Ray, and for Sanofi -Aven s. He is also looking a er the quality of Novamed Healthcare, the nutraceu cal and cosmeceu cal manufacturing plant. 

Abstract:

High Performance Liquid Chromatography (HPLC) is an integral analy cal tool in assessing drug product stability. HPLC methods should be able to separate, detect, and quan fy the various drug-related degradants that can form on storage or manufacturing, plus detect and quan fy any drug-related impuri es that may be introduced during synthesis. Forced degrada on studies of new chemical en  es and drug products are essen al to help develop and demonstrate the specifi city of such stability indica ng methods. In addi on to demonstra ng specifi city, forced degrada on studies can be used to determine the degrada on pathways and degrada on products that could form during storage, and facilitate during formula on, development, manufacturing and packaging. For marke ng applica ons, current FDA and ICH guidance recommends inclusion of the results, including chromatograms of stressed samples, demonstra on of the stability-indica ng nature of the analy cal procedures, and the degrada on pathways of the API in solid state, solu on, and drug product. A review of literature reveals that a large number of methods reported over the period of last 3 – 4 decades under the nomenclature ‘stability-indica ng’, but most of the reported methods fall short in mee ng the current regulatory requirements. Hence a systema c approach for the development of validated SIAMs that should meet the current ICH and regulatory requirements. The following will provide some sugges ons for performing forced degrada on studies based upon available guidance from the ICH and FDA.

Keynote Forum

Humayun Riaz

Rashid Latif College of Pharmacy, Pakistan

Keynote: Antiviral activity of green silver nanoparticles produced using aqueous buds extract of Syzygium Aromaticum

Time : 11:00-11:45

Pharma Research 2020 International Conference Keynote Speaker Humayun Riaz photo
Biography:

Humayun Riaz completed his BPharm & MPhil Pharmaceu cs from Faculty of Pharmacy, University of The Punjab, Pakistan, and MBA Marke ng, PhD Pharmaceu cs from University of Sargodha, Pakistan. He is the prolifi c professional, has got more than 26 years of professional and teaching experience in Pharmacy profession. Currently, he is working as CEO in Oxy Pharma, Marke ng Manager NovaMed Pharmaceu cals (Private) Ltd and Principal/Professor of pharmaceu cs in Rashid La f College of Pharmacy, Pakistan. His areas of exper se are teaching, pharmaceu cals marke ng, leadership, launching of new products, administra on, marke ng strategy, communica on, team building, analysis, mul -tasking, nego a on,  me management, workload distribu on, confl ict resolu on. He has 41 Publica ons in na onal and interna onal journals, he also contributes a chapter in “A compendium of essays on alterna ve therapy intech” and a chapter in “Alterna ve and tradi onal medicines and systems in Pakistan; History, regula on, trends, usefulness, challenges, prospects and limita ons”. 

Abstract:

Poultry is the second gigan c industry of Pakistan but because of various bacterial and viral diseases its progress was aff ected, the most noteworthy ailment is Newcastle disease. Clove enhances the immunity of a human body. This study was performed to assess the immune provoca ve ac vity of Syzygium Aroma cum Extracts (SAE) against Newcastle Disease (ND). ND is an ailment which is accountable for enormous depriva on in unvaccinated rural chicken inhabitant in Pakistan. In current inves ga on, the an viral ac vity of clove buds silver nanopar cles was inspected in-vitro and in-ovo. Embryonated chicken eggs were used to perform the cytotoxicity assay of the Clove Extract Silver Nanopar cles (CESN). We designed the green-synthesis of silver nanopar cles (AgNP) as a novel and eff ectual tool against the ND virus. Syzygium Aroma cum Extract was used as reducing and stabilizing agent for synthesis of AgNP. AgNP was characterized using diversity of biophysical methods inclusive of UV–VISIBLE spectroscopy, Fourier transform infrared spectroscopy (FTIR), TEM, X-ray diff rac on (XRD) and sorted for size categories. AgNP showed in-vitro an viral ac vity against ND virus in embryonated eggs.
 

Keynote Forum

Muhammad Jehangir

Novamed Group, Pakistan

Keynote: Cleaning validations in pharmaceutical industry

Time : 11:45-12:30

Pharma Research 2020 International Conference Keynote Speaker Muhammad Jehangir photo
Biography:

Muhammad Jehangir has 15 years diversifi ed experience of quality control, quality assurance, registra on aff airs, product development and pharmaceu cal manufacturing, process planning, method development, method valida on, sta s cal methodology, process & cleaning valida on, and equipment valida on etc. Cer fi cate courses on cGMP, cGLP, process valida on, CTD documents, ISO 9001:2008, 13485-2003, 14001-2004 and 17025:2017 have strong scien fi c, analy cal, sta s cal, managerial and training skills. Currently, he is working as a Senior Manager Quality Control and valida on for Novamed Pharmaceu cals, Pakistan. It is toll manufacturing oriented company, manufacturing of companies like Getz Pharma, ICI, SEARLE, Macter, Ray, and for Sanofi -Aven s. He is also looking a er the quality of Novamed healthcare, the nutraceu cal and cosmeceu cal manufacturing plant. 

Abstract:

Pharmaceu cal Manufacturers must validate their cleaning process to ensure complies with cGMP regula ons. Minimizing equipment down me has the poten al to impact the effi  ciency and economics of pharmaceu cal produc on. The main purpose of cleaning valida on is to prove the eff ec veness and consistency of cleaning in a given pharmaceu cal produc on equipment to prevent cross contamina on and adultera on of drug products with other ac ve ingredients like unintended compounds or microbiological contamina on leads to prevent several serious problems and also useful in related studies like packaging component cleaning valida on. So it is necessary to validate the cleaning procedures to ensure safety, effi  cacy, quality of the subsequent batches of drug product and regulatory requirements in Ac ve Pharmaceu cal Ingredients (API) product manufacture. The benefi ts due to cleaning valida on are compliance with federal regula ons, iden fi ca on and correc on of poten al problems, previously unsuspected which could compromise the safety and effi  cacy of drug products. In this ar cle cleaning valida on and importance are discussed in briefl y.